Cold-induced hyperphagia requires AgRP neuron activation in mice
نویسندگان
چکیده
منابع مشابه
Cold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in 1-AMPK / mice
Jake D. Bauwens, Eric G. Schmuck, Christopher R. Lindholm, Rebecca L. Ertel, Jacob D. Mulligan, Ian Hovis, Benoit Viollet, and Kurt W. Saupe Departments of Medicine and Physiology, University of Wisconsin, Madison, Wisconsin; and Institut Cochin, Université Paris Descartes, Centre National de la Recherche Scientifique UMR8104, Institut National de la Santé et de la Recherche Médicale U1016, Par...
متن کاملCold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in α₁-AMPK-/- mice.
Recent studies indicate that a substantial amount of metabolically active brown adipose tissue (BAT) exists in adult humans. Given the unique ability of BAT to convert calories to heat, there is intense interest in understanding the regulation of BAT metabolism in hopes that its manipulation might be an effective way of expending excess calories. Because of the established role of AMP-activated...
متن کاملAgrp neuron activity is required for alcohol-induced overeating
Alcohol intake associates with overeating in humans. This overeating is a clinical concern, but its causes are puzzling, because alcohol (ethanol) is a calorie-dense nutrient, and calorie intake usually suppresses brain appetite signals. The biological factors necessary for ethanol-induced overeating remain unclear, and societal causes have been proposed. Here we show that core elements of the ...
متن کاملCorrigendum: Agrp neuron activity is required for alcohol-induced overeating
This corrects the article DOI: 10.1038/ncomms14014.
متن کاملDiazepam-induced hyperphagia in mice is sensitive to quinpirole.
The present trial examined the possibility that diazepam (DZP, 1 mg/kg) induces hyperphagia by acting on the dopaminergic system. Quinpirole (QP), dopamine D-2 receptor agonist, was used for this purpose. Mice fasted for 24 hr were treated with QP 1 (QP-1) or 2 (QP-2) mg/kg 30 min prior to termination of the starvation. DZP was given to untreated mice and half of the QP-1 and QP-2 treated mice ...
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ژورنال
عنوان ژورنال: eLife
سال: 2020
ISSN: 2050-084X
DOI: 10.7554/elife.58764